caffeic acid phenethyl ester and cancer patients

IJMS

Caffeic Acid Phenethyl Ester Is a Potential Therapeutic Agent for Oral Cancer by Ying-Yu Kuo 1 2 3 † Wai-Tim Jim 4 5 6 † Liang-Cheng Su 1 † Chi-Jung Chung 7 Ching-Yu Lin 1 Chieh Huo 1 8 Jen-Chih Tseng 1 3 9 Shih-Han Huang 1 8 Chih-Jen Lai 1 Bo-Chih Chen 1 3 9 Bi-Juan Wang 1 3 9 Tzu-Min Chan 10 11 Hui-Ping Lin 12 Wun-Shaing Wayne Chang 12

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CAPE (Caffeic Acid Phenethyl Ester)

CAPE (caffeic acid phenethyl ester) was the major anticancer ingredient in a propolis sample from Israel (Grunberger et al 1988) CAPE is a derivative of caffeic acid (CA) that down-regulates the GTPase Rac a direct activator of the kinase PAK1 (Xu et al 2005) As a consequence CAPE eventually inactivates PAK1 In-

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PROPOLIS CANCER – Propolis Science

• Caffeic acid phenethyl ester synergistically enhances docetaxel and paclitaxel cytotoxicity in prostate cancer cells * • Anticancer activity of Indian stingless bee propolis: an in vitro study * – PDF Available • Caffeic Acid phenethyl ester inhibits epithelial-mesenchymal transition of human pancreatic cancer cells *

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IJMS

Caffeic Acid Phenethyl Ester Is a Potential Therapeutic Agent for Oral Cancer by Ying-Yu Kuo 1 2 3 † Wai-Tim Jim 4 5 6 † Liang-Cheng Su 1 † Chi-Jung Chung 7 Ching-Yu Lin 1 Chieh Huo 1 8 Jen-Chih Tseng 1 3 9 Shih-Han Huang 1 8 Chih-Jen Lai 1 Bo-Chih Chen 1 3 9 Bi-Juan Wang 1 3 9 Tzu-Min Chan 10 11 Hui-Ping Lin 12 Wun-Shaing Wayne Chang 12

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Caffeic acid phenethyl ester suppresses androgen receptor

Keywords: Caffeic acid phenethyl ester AR CDK1 AKT Prostate cancer Background Androgen receptor (AR) is an androgen-activated tran-scription factor belongs to the nuclear receptor superfam-ily [1] Binding of androgen to AR induces dissociation of AR from heat-shock proteins (HSPs) and stimulates AR phosphorylation [2] AR dimerizes

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Caffeic acid phenethyl ester as an adjuvant therapy for

Caffeic acid phenethyl ester as an adjuvant therapy for advanced prostate cancer Med Hypotheses 2013 80(5):617-9 (ISSN: 1532-2777) Liu CC Hsu JM Kuo LK Chuu CP Prostate cancer is the second most frequently diagnosed cancer of men Androgen ablation therapy is the primary treatment for metastatic prostate cancer However the majority of prostate cancer patients

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Review Article Caffeic Acid Phenethyl Ester and

Review Article Caffeic Acid Phenethyl Ester and Therapeutic Potentials stress in ammation cancer diabetes neurodegeneration and anxiety [ ] ese therapeutic characteristics of CAPE have been summarized in this review article 2 Activities of CAPE Large number of studies has been conducted on various features of the biological and pharmacological activities

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Caffeic Acid Versus Caffeic Acid Phenethyl Ester in the

Epithelium mammary carcinoma is a cancer with a high death rate among women One factor having a significant impact on metastasis is cell migration The aim of this study was to compare migration rate inhibition of caffeic acid (CA) and its phenethyl ester (CAPE) on MCF-7 breast cancer cells Microscopic evaluation was used to determine the

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Caffeic Acid Phenethyl Ester (CAPE) derived

Caffeic acid phenethyl ester (CAPE) is one of the main medicinal components of propolis a honeybee-derived natural product CAPE possesses important biological activities including antibacterial antiviral antioxidant anti-inflammatory and anti-cancer [18 19 20 21]

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Effects of Propolis and Caffeic Acid Phenethyl Ester

Caffeic Acid Phenethyl Ester (CAPE) derived from propolis also possesses a variety of pharmacological properties including anticancer activity Breast cancer the most frequently diagnosed neoplasia and the leading cause of cancer death in women worldwide is a heterogeneous disease with different clinical presentation evolution and response to treatment

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Caffeic acid phenethyl ester suppresses androgen receptor

Keywords: Caffeic acid phenethyl ester AR CDK1 AKT Prostate cancer Background Androgen receptor (AR) is an androgen-activated tran-scription factor belongs to the nuclear receptor superfam-ily [1] Binding of androgen to AR induces dissociation of AR from heat-shock proteins (HSPs) and stimulates AR phosphorylation [2] AR dimerizes

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Caffeic Acid Phenethyl Ester Induces Apoptosis of

Aims: This study aimed to investigate the effect of caffeic acid phenethyl ester (CAPE) an active component isolated from honeybee propolis in inducing apoptosis in human pancreatic cancer cells Methods: Inhibition of viability of BxPC-3 and PANC-1 cell lines induced by CAPE was estimated by a trypan blue dye exclusion test

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Honeybee Propolis Benefits: New Ally In The War On Cancer

Researchers from the University of Chicago Medical Center intrigued by propolis benefits like its anti-cancer potential decided to look at one of its bioactive components caffeic acid phenethyl ester (CAPE) and its impact on human prostate cancer cells In cells grown in a lab even small doses of CAPE slowed the growth of tumor cells And

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Caffeic acid phenethyl ester attenuates changes in

Caffeic acid phenethyl ester attenuates changes in pancreatic tissue damage biomarkers induced by cisplatin Biljana Stošić a b Radmilo Janković a b Marija Stošić b Danica Marković b Ines Veselinović b Ivan Ilić c Dušan Sokolović d a Department of Anesthesiology Faculty of Medicine University of Niš Niš Serbia

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The Efficacy and Safety of Caffeic Acid for Esophageal

In CA group patients will receive coffeic acid treatment: 100-200mg tid po 2 weeks treated then 1 week black interval(weight 50kg 200mg per time weight or =50kg 100mg per time) in placebo group the same shape placebo tablets will be deliveried to patients 1 years follow-up for both groups patients Patients in both arms can receive any other ways of anti cancer therapy in

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Honeybee Propolis Benefits: New Ally In The War On Cancer

Researchers from the University of Chicago Medical Center intrigued by propolis benefits like its anti-cancer potential decided to look at one of its bioactive components caffeic acid phenethyl ester (CAPE) and its impact on human prostate cancer cells In cells grown in a lab even small doses of CAPE slowed the growth of tumor cells And

Get More

Caffeic Acid Phenethyl Ester Induces Apoptosis of

Aims: This study aimed to investigate the effect of caffeic acid phenethyl ester (CAPE) an active component isolated from honeybee propolis in inducing apoptosis in human pancreatic cancer cells Methods: Inhibition of viability of BxPC-3 and PANC-1 cell lines induced by CAPE was estimated by a trypan blue dye exclusion test The type of cell death in BxPC-3 after

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IJMS

Caffeic acid phenethyl ester (CAPE) is one of the most bioactive components extracted from honeybee hive propolis [26 27] CAPE treatment exhibits anti-carcinogenic anti-inflammatory anti-viral and immuno-modulatory properties Several recent studies indicate that CAPE treatment suppresses proliferation survival and invasion of human oral cancer cells We

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Comparison of Two Components of Propolis: Caffeic Acid (CA

50 patients [1-4] 68 Caffeic acid phenethyl ester (CAPE) is the one of the polyphenol which is a component of 69 honeybee propolis Known CAPE properties are antiviral anti-inflammatory anti-cancer and 70 antioxidant effects [17-19] 71 CAPE showed its anticancer effects on different ca ncer cell lines however it exhibited differen-72 tial cytotoxic activity against cancer normal

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Caffeic acid phenethyl ester attenuates changes in

Caffeic acid phenethyl ester attenuates changes in pancreatic tissue damage biomarkers induced by cisplatin Biljana Stošić a b Radmilo Janković a b Marija Stošić b Danica Marković b Ines Veselinović b Ivan Ilić c Dušan Sokolović d a Department of Anesthesiology Faculty of Medicine University of Niš Niš Serbia

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Caffeic Acid Phenethyl Ester Induces Apoptosis of

Aims: This study aimed to investigate the effect of caffeic acid phenethyl ester (CAPE) an active component isolated from honeybee propolis in inducing apoptosis in human pancreatic cancer cells Methods: Inhibition of viability of BxPC-3 and PANC-1 cell lines induced by CAPE was estimated by a trypan blue dye exclusion test The type of cell death in BxPC-3 after

Get More

Honeybee Propolis Benefits: New Ally In The War On Cancer

Researchers from the University of Chicago Medical Center intrigued by propolis benefits like its anti-cancer potential decided to look at one of its bioactive components caffeic acid phenethyl ester (CAPE) and its impact on human prostate cancer cells In cells grown in a lab even small doses of CAPE slowed the growth of tumor cells And

Get More

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