1 3-di-o-tolyguanidine

Guanidine N N'

IUPAC Standard InChIKey: OPNUROKCUBTKLF-UHFFFAOYSA-N CAS Registry Number: 97-39-2 Chemical structure: This structure is also available as a 2d Mol file Other names: Guanidine 1 3-di-o-tolyl- Di-o-tolylguanidine DOTG Eveite DOTG N N'-Di-o-tolylguanidine Vulkacit DOTG Vulkacite DOTG 1 3-Bis(o-tolyl)guanidine 1 3-di-o-Tolylguanidine USAF A-6598 1 3-Di-o-tolyguanidine

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TREATMENT WITH SIGMA RECEPTOR AGONISTS POST

Activation of sigma receptors can ameliorate [Ca2+]i dysregulation associated with ischemia in cortical neurons providing neuroprotective properties The effects of 1 3-di-o-tolyguanidine (DTG) a high affinity sigma receptor agonist as a potential treatment for decreasing infarct area at delayed time points was further examined in rats DTG

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The effect of 'two hit' neonatal and young

pindolol (Sigma) and 0 5 mmolL-1 of 1 3-di-o-tolyguanidine (Sigma) for TB and additional 10 mmolL-1 of (-)-sulpiride (Sigma) for NSB (Figure 1 right panel) The reported K D value for dopamine D 2 receptors is between 0 1 and 0 6 nmolL-1 (Cox and Waszczak 1991 Yokoyama et al 1994 Unis et al 1998) and our ligand concentration which has also been used by others

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BPS Publications

Both radiolabelled slides and [3 H] microscales were apposed to a BAS‐TR2025 phosphoimaging plate (Fuji Imaging Plates Berthold Australia) for 6 days at room temperature On the scanned image relevant brain areas were identified and outlined on the computer screen using the dopamine D 1 and D 2 receptor density pattern (see Figure 1) and a brain atlas (Paxinos and

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Autoradiographic distribution of sigma receptors in

Autoradiographic distributions of [3 H] 1 3-di-O-tolyguanidine [3 H]DTG binding to sigma (σ) receptors were studied in key human brain regions High densities occurred in the substantia nigra pars compacta and cerebellum Pineal and pituitary levels were moderate

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Agent Wanted In Saudi Arabia Rubber Industry Tyre

Agent Wanted In Saudi Arabia Rubber Industry Tyre Industry Low Price Accelerator Dpg Guanidines Find Complete Details about Agent Wanted In Saudi Arabia Rubber Industry Tyre Industry Low Price Accelerator Dpg Guanidines Agent Wanted Rubber Industry Tyre Industry from Plastic Auxiliary Agents Supplier or Manufacturer-Dalian Richon Chem Co Ltd

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Loss of sigma binding sites in the CA1 area of the

The densities of [3 H]1 3-di-o-tolyguanidine ([3 H]DTG) binding to sigma sites in the CA1 stratum pyramidale region in 7 hippocampi affected by Alzheimer's disease were compared with densities in 7 normal hippocampi There was an average reduction of 26% in [3 H]DTG binding in this area which was correlated with an average 29% pyramidal cell loss in the same region

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Sigma Receptor Activation Reduces Infarct Size at 24

We examined the effects of 1 3-di-o-tolyguanidine (DTG) a high affinity sigma receptor agonist as a potential treatment for decreasing infarct area at delayed time points Rats were subjected to permanent embolic middle cerebral artery occlusion (MCAO) and allowed to recover before receiving subcutaneous injections of 15 mg/kg of DTG at 24

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Autoradiographic distribution of sigma receptors in

Autoradiographic distributions of [3 H] 1 3-di-O-tolyguanidine [3 H]DTG binding to sigma (σ) receptors were studied in key human brain regions High densities occurred in the substantia nigra pars compacta and cerebellum Pineal and pituitary levels were moderate

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US Patent Application for Treatment with Sigma Receptor

A method of post-stroke treatment at delayed timepoints with sigma receptor agonists Sigma receptors are promising targets for neuroprotection following ischemia One of the key components in the demise of neurons following ischemic injury is the disruption of intracellular calcium homeostasis The sigma receptor agonist DTG was shown to depress [Ca2+]i

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촉진제 가황촉진제 Vulcanization Accelerator

고무배합약품 고무첨가제 rubber additive 카본블랙 carbon black 도전성 카본블랙 conductivity carbon black antistatic carbonblack 케첸블랙 Ketjenblack EC 촉진제 accelerator 노화방지제 antioxidant 가황제 vulcanizing agent 가교제 crosslinking agent 가교조제 coagent co-crosslinking agent 특수 촉진제 special accelerator 금속산화물

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Guanidine N N'

Notice: Except where noted spectra from this collection were measured on dispersive instruments often in carefully selected solvents and hence may differ in detail from measurements on FTIR instruments or in other chemical environments More information on the manner in which spectra in this collection were collected can be found here Notice:

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Guanidine N N'

Notice: Except where noted spectra from this collection were measured on dispersive instruments often in carefully selected solvents and hence may differ in detail from measurements on FTIR instruments or in other chemical environments More information on the manner in which spectra in this collection were collected can be found here Notice:

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Sigma Receptor Activation Reduces Infarct Size at 24

We examined the effects of 1 3-di-o-tolyguanidine (DTG) a high affinity sigma receptor agonist as a potential treatment for decreasing infarct area at delayed time points Rats were subjected to permanent embolic middle cerebral artery occlusion (MCAO) and allowed to recover before receiving subcutaneous injections of 15 mg/kg of DTG at 24

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Guanidine N N'

IUPAC Standard InChIKey: OPNUROKCUBTKLF-UHFFFAOYSA-N CAS Registry Number: 97-39-2 Chemical structure: This structure is also available as a 2d Mol file Other names: Guanidine 1 3-di-o-tolyl- Di-o-tolylguanidine DOTG Eveite DOTG N N'-Di-o-tolylguanidine Vulkacit DOTG Vulkacite DOTG 1 3-Bis(o-tolyl)guanidine 1 3-di-o-Tolylguanidine USAF A-6598 1 3-Di-o-tolyguanidine

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GB891537A

Powdered organic chemical substances which are rubber accelerators retarders or antioxidants are shaped into pellets or granules by the use of a polymer of tetrafluoroethylene as binding agent Substances specified are 2-mercapto benzthiazole dibenzthiazyl disulphide N-cyclohexylbenzthiazyl-2-sulphenamide N-tertiary-butyl benzthiazyl-2-sulphenamide N-tertiary

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Sigma

Discovery of a role for sigma-1 in switching between passive and active threat responses opens up new avenues for investigation of this enigmatic receptor Additional studies will be required to elucidate the precise mechanisms by which sigma-1 regulates threat responses including the neuronal circuits involved the cellular signaling events

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US9550893B2

The invention relates to a rubber composition prepared with pre-treated precipitated silica and tire with component comprised of such rubber composition The rubber composition is comprised of at least one diene-based elastomer and said pre-treated precipitated silica together with a sulfur cure package comprised of elemental sulfur together with 1 6-bis (N N′

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Loss of sigma binding sites in the CA1 area of the

The densities of [3 H]1 3-di-o-tolyguanidine ([3 H]DTG) binding to sigma sites in the CA1 stratum pyramidale region in 7 hippocampi affected by Alzheimer's disease were compared with densities in 7 normal hippocampi There was an average reduction of 26% in [3 H]DTG binding in this area which was correlated with an average 29% pyramidal cell loss in the same region

Get More

촉진제 가황촉진제 Vulcanization Accelerator

고무배합약품 고무첨가제 rubber additive 카본블랙 carbon black 도전성 카본블랙 conductivity carbon black antistatic carbonblack 케첸블랙 Ketjenblack EC 촉진제 accelerator 노화방지제 antioxidant 가황제 vulcanizing agent 가교제 crosslinking agent 가교조제 coagent co-crosslinking agent 특수 촉진제 special accelerator 금속산화물

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