benzyl alcohol metabolism test

Ferrlecit

Benzyl Alcohol Toxicity and Pediatrics Ferrlecit is not approved for use in neonates or infants Serious adverse reactions including fatal reactions and the gasping syndrome occurred in premature neonates and low-birth-weight infants in the neonatal intensive care unit who received drugs containing benzyl alcohol as a preservative

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BENZYLACETATE 1 Exposure Data

4 1 Absorption distribution metabolism and excretion The metabolism of benzyl acetate involves very rapid hydrolysis to acetate and benzyl alcohol The latter is subsequently mainly oxidized to benzaldehyde and benzoic acid A small part of the benzyl alcohol may be conjugated with sulfate leading

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Natural Preservatives for Cosmetics: Why When

Benzyl alcohol is an organic compound It is used typically in concentrations from 0 3 – 2% which is a lot but it is a very effective preservative Therefore a lot of effort was invested by chemists to find a combination that will allow the reduction of the concentration of benzyl alcohol

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Safety Assessment of Benzyl Alcohol Benzoic Acid and

Benzyl alcohol benzoic acid and its (number and breed not stated) small amounts of hippuric acid were detected in the 24-hour urine The metabolism of benzyl benzoate to benzoic acid in vivo has The ocular toxicity of benzyl alcohol was evaluated using 9 New Zealand rabbits 80 The following test concentrations of benzyl alcohol

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benzyl alcohol 100

Benzyl alcohol appears in many flower and herb GC and headspace analyses and appears to act as a natural fixative and blending agent in flower scents: Genotoxicity testing of four benzyl derivatives in the Drosophila wing spot test Intestinal SGLT1-mediated absorption and metabolism of benzyl beta-glucoside contained in Prunus mume:

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868 Benzyl acetate (WHO Food Additives Series 37)

These results suggest that cytochrome P450 but not catalase or alcohol dehydrogenase is responsible for the metabolism of benzyl alcohol to benzaldehyde in human liver microsomes Benzyl alcohol does not appear to be metabolized by microsomal enzymes in

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What Are the Causes of a False Positive in ETS or ETG

Many schools and employers employ drug testing EtS and EtG urine tests measure a product that results from the breakdown of alcohol These tests are sensitive to alcohol consumed up to 80 hours previously However a number of conditions increase the risk of

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BENZOIC ACID AND SODIUM BENZOATE

The International Programme on Chemical Safety (IPCS) established in 1980 is a joint venture of the United Nations Environment Programme (UNEP) the International Labour Organization (ILO) and the World Health Organization (WHO) The overall objectives of the IPCS are to establish the

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Metabolism of Odorant Molecules in Human Nasal/Oral

Abstract In this study we examined the mode of metabolism of food odorant molecules in the human nasal/oral cavity in vitro and in vivo We selected 4 odorants 2-furfurylthiol (2-FT) hexanal benzyl acetate and methyl raspberry ketone which are potentially important for designing food flavors

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Benzoic acid

Benzoic acid is a precursor to benzoyl chloride C 6 H 5 C(O)Cl by treatment with thionyl chloride phosgene or one of the chlorides of phosphorus Benzoyl chloride is an important starting material for several benzoic acid derivates like benzyl benzoate which is used in artificial flavours and insect repellents Niche and laboratory uses

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"Inactive" Ingredients in Pharmaceutical Products: Update

Because of an increasing number of reports of adverse reactions associated with pharmaceutical excipients in 1985 the Committee on Drugs issued a position statement[1][1]recommending that the Food and Drug Administration mandate labeling of over-the-counter and prescription formulations to include a qualitative list of inactive ingredients

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Metabolism of butyl benzyl phthalate by Gordonia sp

12-9-2003On the other hand the test organism grew well on benzyl alcohol and butanol the hydrolyzed products of BBP The esterase(s) was found to be inducible in nature and can hydrolyze in vitro the seven different phthalate diesters tested to their corresponding monoesters irrespective of their support to the growth of the test organism PMID: 12943660

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Food and Chemical Toxicology

Bronaugh et al 1990: The skin absorption of [7e14C] benzyl acetate was measured in 4 rhesus monkeys The test material in acetone was applied at a concentration of 4 mg/ cm2 to a 1 cm2 area of abdominal skin for 24 h Urine was collected for an additional 4 days The extent of dermal ab-sorption was estimated from the amount of 14C

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Alcohol Toxicity Workup: Laboratory Studies Osmolar Gap

1-11-2018Although any alcohol can be toxic if ingested in large enough quantities the term toxic alcohol has traditionally referred to isopropanol methanol and ethylene glycol Prompt recognition and treatment of patients intoxicated with these substances can reduce the morbidity and mortality associated with these alcohols

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Alcohol Metabolites Quantitative Urine

How long after alcohol exposure are alcohol metabolites present in the urine? EtG may be present in the urine for up to 80 hours after ethanol ingestion EtS may be detectable for 24 hours or more after ingestion These times depend on the cutoff used for the test and the patient's metabolic rate and the time and duration of alcohol exposure

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Metabolism of butyl benzyl phthalate by Gordonia sp

Read Metabolism of butyl benzyl phthalate by Gordonia sp strain MTCC 4818 Biochemical and Biophysical Research Communications on DeepDyve the largest online rental service for scholarly research with thousands of academic publications available at your fingertips

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SOLU

benzyl alcohol administered The amount of benzyl alcohol at which toxicity may occur is not known If the patient requires more than the recommended dosages or other medications containing this preservative the practitioner must consider the daily metabolic load of benzyl alcohol from these combined sources (see

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Food and Chemical Toxicology

6 Metabolism Chidgey et al (1986): The metabolism of benzyl acetate was investigated in male Fischer 344 rats Rats were dosed by gavage with [methylene-(14)C] benzyl acetate (500 mg/kg) alone or together with metabolic inhibitors Benzyl acetate is rapidly hy-drolyzed to benzyl alcohol which is oxidized to benzaldehyde and

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